Thu May 25 20:18:43 +08 2017  
SINGAPORE
GUM™
    HPV Vaccine
SINGAPORE GUM™
HIV PEP (post-exposure prophylaxis): Stop HIV infection within 3 days after unprotected sex.
HIV test: 20 minute rapid test to accurately detect HIV infection 28 days after unprotected sex.
STD testing: Full & comprehensive sexually transmitted disease testing.

HPV Vaccine | SINGAPORE GUM™

Summary

HPV Vaccine | SINGAPORE GUM™ @singaporegum_com: Human papillomavirus (HPV) vaccine jab/shot/injection schedule, to vaccinate against the HPV, to immunise against cervical/penile/anal/mouth/throat cancer and genital warts, Singapore. Private & confidential service.

Advertisement: Come to sunny Singapore to have your testing and treatment. Singapore Ministry of Health registered general practice (GP) clinic:
SHIM CLINIC
SINGAPORE GUM™
168 Bedok South Avenue 3 #01-473
Singapore 460168
Tel: (+65) 6446 7446
Fax: (+65) 6449 7446
24hr Answering Tel: (+65) 6333 5550
Web: www.shimclinic.com
Opening Hours
Monday to Friday: 9 am to 3 pm, 7 pm to 11 pm
Saturday & Sunday: 7 pm to 11 pm
Public Holidays: Closed
Last registration: one hour before closing time.
Walk-in clinic. Appointments not required.
Bring NRIC, Work Pass or Passport for registration.

Description

Table of Contents

Since 2006, two HPV vaccines have been licensed; one vaccine targets four and the other two HPV genotypes. Both vaccines are designed to protect against about 70% of cervical cancer cases worldwide (the 4-valent vaccine also protects against genital warts). The vaccines are intended for use primarily in adolescent girls aged 10–14 years. The complete series of quadrivalent vaccine is administered at day 0; 2 months; and 6 months. The bivalent vaccine is administered at day 0; 1 month; and 6 months. Repeating previous doses is not necessary if the 3-dose programme has been interrupted. Booster doses are currently not recommended. Over the next few years, HPV vaccination will be introduced into the immunization schedules of several countries.

HPV vaccine (previously known as cervical cancer vaccine) types:

  • Gardasil® [HPV (Human Papillomavirus) Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant]
  • Cervarix® [HPV (Human Papillomavirus) Bivalent (Types 16 and 18) Vaccine, Recombinant]
  • V503 [HPV (Human Papillomavirus) Nonavalent (Types 6, 11, 16, 18, 31, 33, 45, 52, and 58) Vaccine, Recombinant]
References Gardasil® [HPV (Human Papillomavirus) Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant] References Cervarix® [HPV (Human Papillomavirus) Bivalent (Types 16 and 18) Vaccine, Recombinant] References V503 [HPV (Human Papillomavirus) Nonavalent (Types 6, 11, 16, 18, 31, 33, 45, 52, and 58) Vaccine, Recombinant] - to be released in 2013 STD vaccine / hepatitis vaccine shot/jab/injection to prevent some STDs

Vaccine Against Disease Age D
o
s
e
s
Dose schedule Price
per
dose
(SG$)
Havrix™ 1440 Adult Hepatitis A virus Hepatitis A ≥19y 2 m 0 & 6-12 $90/=
Twinrix® Hepatitis A virus
Hepatitis B virus
Hepatitis A
Hepatitis B
1-15y 2 m 0, 6-12 $135/=
≥16y 3 m 0, 1, 6
4 d 0, 7, 21 & m 12
Inactivated / Fractional / Protein / Subunit / Recombinant
Engerix™-B 20 μg Hepatitis B virus Hepatitis B 11-15y 2 m 0, & 6 $50/=
≥20y 3 m 0, 1, & 6
4 m 0, 1, 2, & 12 or
d 0, 7, 21 & m 12
Gardasil® HPV
types 6, 11, 16, & 18
Genital warts
Cervical cancer
9-26y 3 m 0, 2, & 6 or
m 0, 1, & 4
$195/=
Cervarix® HPV
types 16, & 18
(31, 33, & 45)
10-25y 3 m 0, 1, & 6
m 0, 1, & 5
m 0, 2½, 12
$195/=
V503 HPV
types 6, 11, 16, 18,
31, 33, 45,
52, & 58
3 m 0, 2, & 6 or
m 0, 1, & 4
$???/=

HPV test for men/women.

  • Digene® High-Risk HPV DNA Test
  • Digene® HPV DNA Test
  • Digene® HPV Genotyping PS Test
  • Hybribio®
    • HPV GenoArray Test Kit
    • Detects 15 high-risk HPV types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, and 68. And 6 low-risk HPV types: 6, 11, 42, 43, 44, CP8304
    • Able to differentiate which types are positive.
    • May be available in Singapore soon.
  • Cobas® HPV Test
    • Cobas® HPV Test
    • Detects 14 high-risk HPV types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68
    • The test specifically identifies (types) HPV 16 and HPV 18, while concurrently detecting the rest of the high risk types (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68)
    • Cost is SG$200/=
  • LINEAR ARRAY® HPV Genotyping Test
    • LINEAR ARRAY® HPV Genotyping Test
    • Identifies 37 high-risk HPV genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68, 73 (MM9), 82 (MM4) low-risk HPV genotypes 6, 11, 26, 40, 42, 53, 54, 55, 61, 62, 64, 67, 69, 70, 71, 72, 81, 83 (MM7), 84 (MM8), IS39, and CP6108
  • INNO-LiPA HPV Genotyping Extra
    • INNO-LiPA HPV Genotyping Extra
    • Identifies 15 high-risk HPV genotypes (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 73, 82) 3 probable high-risk HPV genotypes (26, 53, 66) 7 low-risk HPV genotypes (6, 11, 40, 43, 44, 54, 70) and some additional types (69, 71, 74).
  • PapilloCheck®
    • PapilloCheck®
    • Identifies 24 hiv-risk HPV types 16 18 31 33 35 39 45 51 52 53 56 58 59 66 68 70 73 82 and low-risk HPV types 6 11 40 42 43 44

HPV / human papillomavirus.

  • 120 known human papillomavirus (HPV)
  • 51 HPV types, and 3 subtypes are genital HPV as they infect the genital mucosa.
  • 31 genital HPV types are low risk
  • 6 genital HPV types are intermediate risk
  • 17 genital HPV types are high risk
They cause Genital HPV types, cancer risk, vaccine and test coverage
Type
Species
Risk
Cervarix
Gardasil
Gardasil-9
DigeneHR
DigenePS
CobasHPV
Digene
HybriBio
PapilloCheck
InnoLiPA
LinearArray
61 3 L ----------+-
72 3 L ----------+-
81 3 L -------+--+-
83 3 L ----------+-
84 3 L ----------+-
62 3 L ----------+-
CP6108 3 L ----------+-
71 15 L ---------++-
26 5 H ---------++-
51 5 H ---+-++++++-
69 5 H ---------++-
82 5 H --------+++-
IS39 5 H ----------+-
18 7 H +++++++++++-
39 7 H ---+-++++++-
45 7 H --+++++++++-
59 7 H ---+-++++++-
68 7 H ---+-++++++-
70 7 H --------+++-
53 6 H -------++++-
56 6 H ---+-++++++-
66 6 H -----+-++++-
54 13 L ---------++-
42 1 L ------+++-+-
40 8 L --------+++-
43 8 L ------++++--
6 10 L -++---+++++-
11 10 L -++---+++++-
44 10 L ------++++--
74 10 L ---------+--
16 9 H +++++++++++-
31 9 H --++-++++++-
33 9 H --++-++++++-
35 9 H ---+-++++++-
52 9 H --++-++++++-
58 9 H --++-++++++-
67 9 H ----------+-
73 11 H --------+++-

Legend: 71 (CP 8061), 73/MM9, 81 (CP 8304), 82 (MM4), 82 (IS 39), 83 (MM7), 84 (MM8), 89 (CP 6108)

References

Cervical cancer Genital warts: penile warts / vaginal warts / anal warts / anogenital warts / venereal warts / condyloma / condylomata acuminata / "cauliflower" sex disease.

References

Warts - on male sex organ Genital warts appear within 3 months after sexual contact with an infected person.

Genital warts:

  • are usually soft, pink cauliflower-like growths or flesh-coloured bumps on the sex organs
  • may also be hard and smooth
  • occur alone or in groups
  • tend to recur after treatment
  • increase the risk of cervical cancer in women.


Warts - on female sex organ An infected woman may infect her newborn during childbirth.

A person with genital warts can infect others through sexual contact.



Genital warts treatment / HPV treatment

Sexual risk (of HIV/STD/pregnancy), and what you can do before and after exposure.

Timeline HIV STD Pregnancy
Before exposure
Abstain from sex, Be faithful, or Condom use
Circumcision (males only)
Contraception (females only)
HIV PrEP (pre-exposure prophylaxis) STD vaccine:
- Hepatitis vaccine
- HPV vaccine
STD / HIV exposure
Unsafe sex / unprotected sex:
No condom / Condom broke / Condom slip
0-72 hours HIV prevention
HIV PEP (post-exposure prophylaxis) treatment
- Stop HIV infection after exposure.
STD testing.
If STD symptoms appear, then do STD treatment.
- Males: Do not urinate for at least 4 hours before arriving.
- Females: testing is more accurate when you are not menstruating.
Emergency contraception (females only)
2 weeks HIV DNA PCR test
1 month 20 minute rapid HIV test - SD Bioline HIV Ag/Ab Combo:
- Fingerprick blood sampling.
3 months 20 minute rapid HIV test - OraQuick®:
- Oral saliva or
- Fingerprick blood sampling.
Full & comprehensive STD testing
- Males: Do not urinate for at least 4 hours before arriving.
- Females: testing is more accurate when you are not menstruating.

References


Latest News

Global challenges of implementing human papillomavirus vaccines
Tue, 29 Mar 2016 09:23:40 +0100 | International Journal of Infectious Diseases
Abstract: Every year cervical cancer affects around 528000 women and causes 266000 deaths worldwide with 80% of deaths occurring in less developed countries with a concomitant 18-fold difference in mortality occurring between developed and developing countries. Cervical cancers is caused by the Human Papilloma Virus (HPV) with the oncogenic types 16 and 18 accounting for 70% of invasive disease. Other cancers associated with HPV infection include vaginal, vulvar, penile, oropharyngeal and anal cancers. (Source: International Journal of Infectious Diseases)

Universal HPV Vaccination of Girls Prevents Genital Warts in Young MenUniversal HPV Vaccination of Girls Prevents Genital Warts in Young Men
Mon, 28 Mar 2016 19:39:01 +0100 | Medscape Medical News Headlines
In Denmark, the human papillomavirus (HPV) vaccination program for girls and women has been followed by a decreased incidence of genital warts in young men. Reuters Health Information (Source: Medscape Medical News Headlines)

Mp36-18 high-risk hpv subtypes in squamous cell carcinoma of the scrotum
Mon, 28 Mar 2016 19:24:05 +0100 | The Journal of Urology
Commercially available vaccines against high-risk human papilloma virus (HR-HPV) have been promoted for cervical cancer prevention and more recently marketed towards men for secondary preventative purposes. Previously published data have also focused on the utility of circumcision in the prevention of HPV transmission. Squamous cell carcinoma (SCC) of the scrotum is associated with infection by HR-HPV in a subset of patients. The subtypes of HR-HPV involved in this neoplasm are unknown. (Source: The Journal of Urology)

Influence of Gender and Gender-Specific Recommendations on Adolescent Human Papillomavirus Vaccination
Sun, 27 Mar 2016 22:00:00 +0100 | American Journal of Preventive Medicine
Conclusions Changing HPV vaccine recommendations had minimal cross-gender impact. Early adoption and timely completion patterns were mostly similar across genders. (Source: American Journal of Preventive Medicine)

A Cross-Sectional Study of Human Papillomavirus Vaccine Utilization Among University Women: The Role of Ethnicity, Race, and Risk Factors
Sat, 26 Mar 2016 08:13:15 +0100 | Journal of Lower Genital Tract Disease
Conclusions: Human papillomavirus vaccine is highly acceptable among college women, particularly among Hispanic women. Efforts to vaccinate should include time of college enrollment. Such efforts are critical for the large scale prevention of cervical cancer and its precursor lesions and ultimately for preventable cervical cancer mortality. (Source: Journal of Lower Genital Tract Disease)

Committee Opinion No. 661: Integrating Immunizations Into Practice.
Thu, 24 Mar 2016 18:43:02 +0100 | Obstetrics and Gynecology
Authors:

Committee Opinion No. 661 Summary: Integrating Immunizations Into Practice.
Thu, 24 Mar 2016 18:43:02 +0100 | Obstetrics and Gynecology
Authors:

Primary HPV testing: a proposal for co‐testing in initial rounds of screening to optimise sensitivity of cervical cancer screening
Wed, 23 Mar 2016 23:34:13 +0100 | Cytopathology
This article proposes a compromise: cytology and HPV co‐testing for the first two screening tests to optimise the sensitivity of the test as a whole. Registrations of invasive and in situ carcinoma of the uterine cervix in England indicate that the prevalence of the disease is highest in young women in the early rounds of screening. Calculations of the likely impact on the workload of this proposal have been based on a service evaluation of 295 cytology tests received at St Thomas’ Hospital, which suggests that the volume of cytology tests would be reduced by approximately 60% compared with 80% for primary HPV testing alone. This proposal should be debated openly before irrevocable changes are made to a skilled workforce. (Source: Cytopathology)

Gardasil is destroying young girls' ovaries and reproductive systems
Wed, 23 Mar 2016 06:00:00 +0100 | NaturalNews.com
(NaturalNews) A new study has found that Merck & Co., the maker of the human papillomavirus (HPV) vaccine Gardasil, neglected to examine the drug's effect on the reproductive systems of women.As a result of that neglect, as well as the inherent dangers behind the vaccine, an Australian... (Source: NaturalNews.com)

HPV vaccines are harming and killing victims worldwide in a silent epidemic of medical violence against children
Tue, 22 Mar 2016 06:00:00 +0100 | NaturalNews.com
(NaturalNews) One highly controversial Human Papillomavirus (HPV) vaccine, Gardasil, which is administered to young girls ostensibly to defend against an early onset of the only form of contagious cancer, has actually been responsible for more than 30 deaths, according to the site... (Source: NaturalNews.com)